The signs and symptoms of mesothelioma depend on the location of the tumour, its size and whether it is benign or malignant.- Symptoms occur as the fluid around the affected body organ thickens and prevents surrounding body organs from functioning normally.
| Type of Mesothelioma | Symptoms include: |
| Pleural | Shortness of breath Chest pain Cough |
| Peritoneal | Abdominal pain or swelling |
| Pericardial | Shortness of breath |
| Advanced | Fatigue |

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